Article: Interactions between Inhibitory Interneurons and Excitatory Associational Circuitry in Determining Spatio-Temporal Dynamics of Hippocampal Dentate Granule Cells: A Large-Scale Computational Study.
Full Text (publisher's website) ;
Article Metadata ;
Article Data (extracted)
Hendrickson PJ; Yu GJ; Song D; Berger TW
Front Syst Neurosci, 2015
Table 2
Passive and active biophysical parameters for dentate cells.
Cell Type
Property/mechanism
Soma
GCL
Inner 1/3
Middle 1/3
Outer 1/3
Granule cell
Soma S.A. (cm2)
4.97E-04
Soma volume (cm3)
1.11E-06
R.M.P. (mV)
-75.01
Rin (M-Ohms)
185.86
Membrane time constant (ms)
31
Latency to first AP (ms)
100
Cm (uF/cm2)
9.8
9.8
15.68
15.68
15.68
Ra (ohm-cm)
210
210
210
210
210
Leak (S/cm2)
2.90E-04
2.90E-04
4.57E-04
4.57E-04
4.57E-04
Sodium (S/cm2)
0.84
0.126
0.091
0.056
–
Delayed rectifier K (slow)
0.006
0.006
0.006
0.006
0.008
Delayed rectifier K (fast)
0.036
0.009
0.009
0.00225
0.00225
A-type K (S/cm2)
0.108
–
–
–
–
L-type Ca (S/cm2)
0.0025
0.00375
0.00375
0.00025
–
N-type Ca (S/cm2)
1.47E-03
7.35E-04
7.35E-04
7.35E-04
7.35E-04
T-type Ca (S/cm2)
0.000074
0.00015
0.0005
0.001
0.002
Ca-dependent K (SK)
0.001
0.0004
0.0002
–
–
Ca- and V- dependent K (BK)
1.20E-04
1.20E-04
2.00E-04
4.80E-04
4.80E-04
Tau for decay of Ca (ms)
10
10
10
10
10
Steady-state Ca (mol)
5.00E-06
5.00E-06
5.00E-06
5.00E-06
5.00E-06
Mossy cell
Soma S.A. (cm2)
2.51E-03
Soma volume (cm3)
2.51E-05
R.M.P. (mV)
-64.75
Cm (uF/cm2)
0.6
Ra (ohm-cm)
100
Leak (S/cm2)
1.10E-05
Sodium (S/cm2)
0.12
Delayed rectifier K (fast)
5.00E-04
A-type K (S/cm2)
1.00E-05
L-type Ca (S/cm2)
6.00E-04
N-type Ca (S/cm2)
5.00E-05
Ca-dependent K (SK)
1.60E-03
Ca- and V- dependent K (BK)
1.65E-02
Tau for decay of Ca (ms)
10
Steady-state Ca (mol)
5.00E-06
Inferred neuron-electrophysiology data values
Neuron Type
Neuron Description
Ephys Prop
Extracted Value
Standardized Value
Content Source
